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细胞因子报告基因细胞/趋势因子测试细胞

2023-02-28
浏览次数: 38

细胞因子与免疫系统细胞相互作用可调节宿主对于疾病和感染的反应,并介导正常的细胞过程。InvivoGen提供针对不同细胞因子(干扰素、白细胞介素、TNF和TGF)信号通路的报告基因细胞。所有细胞系的生物活性均经过严格的功能测试分析。另外,InvivoGen也提供一系列细胞因子报告基因细胞,可用于研究在更多严重感染病例中,如SARS-CoV-2引发的高度炎症反应的通路。


细胞系产品名称表达系统报告系统货号
INTERFERONREPORTERCELLS
B16(mouse)B16-Blue™IFN-α/βMousetypeIIFNs(JAK/ISGF3pathway)SEAPbb-ifnt1
B16-Blue™IFN-γMousetypeIIIFN(JAK/STAT-1pathway)SEAPbb-ifng
HEK293(human)HEK-Blue™IFN-α/βHumantypeIIFNs(JAK/ISGF3pathway)SEAPhkb-ifnab
HEK-Blue™IFN-γHumantypeIIIFN(JAK/STAT-1pathway)SEAPhkb-ifng
HEK-Blue™IFN-λHumantypeIIIIFN(JAK/ISGF3pathway)SEAPhkb-ifnl
HEK-Dual™IFN-γHumantypeIIIFN(JAK/STAT-1pathway)SEAP/Luciahkd-ifng
INTERLEUKINREPORTERCELLS
HEK293 (human)HEK-Blue™IL-1βHuman&mouseIL-1β(NF-κB/AP-1pathway)SEAPhkb-il1b
HEK-Blue™IL-1RHuman&mouseIL-1α/β(NF-κB/AP-1pathway)SEAPhkb-il1r
HEK-Blue™IL-2Human&mouseIL-2(STAT-5pathway)SEAPhkb-il2
HEK-Blue™CD122/CD132HumanIL-2&IL-15(STAT-5pathway)SEAPhkb-il2bg
HEK-Blue™IL-4/IL-13HumanIL-4andhuman&mouseIL-13(STAT-6pathway)SEAPhkb-il413
HEK-Blue™IL-5Human&mouseIL-5(STAT-5pathway)SEAPhkb-il5
HEK-Blue™IL-6HumanIL-6(STAT-3pathway)SEAPhkb-hil6
HEK-Blue™IL-7Human&mouseIL-7(STAT-5pathway)SEAPhkb-il7
HEK-Blue™IL-9Human&mouseIL-9(STAT-5pathway)SEAPhkb-il9
HEK-Blue™IL-10HumanIL-10(STAT-3pathway)SEAPhkb-hil10
HEK-Blue™IL-11Human&mouseIL-11(STAT-3pathway)SEAPhkb-il11
HEK-Blue™IL-12Human&mouseIL-12(STAT-4pathway)SEAPhkb-il12
HEK-Blue™IL-17HumanIL-17A/Fandhuman&mouseIL-17E(NF-κB/AP-1pathway)SEAPhkb-il17
HEK-Blue™IL-17CHuman&mouseIL-17C/EandhumanIL-17A(NF-κB/AP-1pathway)SEAPhkb-il17c
HEK-Blue™IL-18Human&mouseIL-18(NF-κB/AP-1pathway)SEAPhkb-hmil18
HEK-Blue™IL-22Human&mouseIL-22(STAT-3pathway)SEAPhkb-hmil22
HEK-Blue™IL-23Human&mouseIL-23(STAT-3pathway)SEAPhkb-hmil23
HEK-Blue™IL-33HumanIL-33reportercells(NF-κB/AP-1pathway)SEAPhkb-hil33
HEK-Blue™IL-36HumanIL-36reportercells(NF-κB/AP-1pathway)SEAPhkb-hil36
TUMORNECROSISFACTORFAMILYCYTOKINES&TUMORGROWTHFACTORREPORTERCELLS
HEK293 (human)HEK-Blue™CD40LHumanCD40L(NF-κBpathway)SEAPhkb-cd40
HEK-Blue™RANKLHuman&mouseRANKL(NF-κB/AP-1pathway)SEAPhkb-rankl
HEK-Blue™TNF-αHuman&mouseTNF-α(NF-κB/AP-1pathway),knockdownofhumanMyD88SEAPhkb-tnfdmyd
HEK-Dual™TNF-αHuman&mouseTNF-α(NF-κB/AP-1pathway),knockdownofhumanMyD88SEAP/Luciahkd-tnfa
HEK-Blue™TGF-βHumanTGF-β(TGFBRI/Smad3/4pathway)SEAPhkb-tgfb
HEK-Blue™TPOHuman&mouseTPO(STAT5pathway)

CHEMOKINETESTCELLS
THP-1(human)THP1-Blue™KI-IP10LuciaknockedintohumanIP10(CXCL10)(parentalcelllineTHP1-Blue™NF-κB)SEAP/Luciathpb-ip10kilc


使用INVIVOGEN细胞因子效应器细胞的优点


  1. 细胞因子生物活性的检测  

  2. 高灵敏度

  3. 成本效益  

  4. 广泛的动态范围

  5. 短暂动手实验

  6. 裸眼视觉化

  7. 适用于药物筛选(普通筛选或高通量筛选,动力学)



详情请联系 Invivogen 全国授权代理-欣博盛生物科技 


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