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Trilink CleanCap® Reagent AG (3' OMe) - (N-7413)产品介绍

2022-03-28
浏览次数: 397

窗体顶端

CleanCap AG (3'OMe)用于mRNA的共转录,m7(3'OMeG)(5')ppp(5')(2'OMeA)pG

 

产品描述:

CleanCap®AG (3' OMe)TriLink公司的专有的共转录加帽试剂,用于5 '帽端mRNA转录,形成Cap 1结构。CleanCap的加帽效率高达98%Trilink N-7413TrilinkCleanCap®Reagent AG共转录产品的cap1mRNA要比 mCAPARCA加帽产生的cap0 mRNA活性更好。


产品信息:

产品货号N-7413
纯度≥95% by AX-HPLC
消光系数30,539 Lmol-1cm-1 at 255 nm
分子式C33H45N15O24P4 (游离酸)
分子质量1159.6
盐形式Na+
浓度100 mM
溶液组分
推荐的储存温度-20°C 或者以下
其他名称CleanCap® Reagent AG(3' OMe) for co-transcriptional capping of mRNA, m7(3'OMeG)(5’)ppp(5')(2'OMeA)pG
应用CRISPR, In vitro Transcription, Recombinases, TALENS, Transposases, Vaccine Development, Zinc Finger Nucleases
主链5'-5'-三磷酸
碱基类似物腺苷酸,鸟苷酸
核苷酸种类帽类似物

 

产品规格如下:

供应商产品编号产品名称规格
TriLinkN-7413-1CleanCap Reagent  AG3'OMe,  1 umole1 umol
TriLinkN-7413-5CleanCap Reagent  AG3'OMe,  5 umole5 umol
TriLinkN-7413-10CleanCap Reagent  AG3'OMe,  10 umole10 umol
TriLinkN-7413-100CleanCap Reagent  AG3'OMe,  100 umole100 umol


文献引用;

● Rothgangl, T;Dennis, MK;Lin, PJC;Oka, R;Witzigmann, D;Villiger, L;Qi, W;Hruzova, M;Kissling, L;Lenggenhager, D;Borrelli, C;Egli, S;Frey, N;Bakker, N;Walker, JA;Kadina, AP;Victorov, DV;Pacesa, M;Kreutzer, S;Kontarakis, Z;Moor, A;Jinek, M;Weissman, D;Stoffel, M;van Boxtel, R;Holden, K;Pardi, N;Th . In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels 

● Weissman, D;Alameh, MG;de Silva, T;Collini, P;Hornsby, H;Brown, R;LaBranche, CC;Edwards, RJ;Sutherland, L;Santra, S;Mansouri, K;Gobeil, S;McDanal, C;Pardi, N;Hengartner, N;Lin, PJC;Tam, Y;Shaw, PA;Lewis, MG;Boesler, C;?ahin, U;Acharya, P;Haynes, BF;Korber, B;Montefiori, DC; . D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization 

● Pandey, RR;Delfino, E;Homolka, D;Roithova, A;Chen, KM;Li, L;Franco, G;V . The Mammalian Cap-Specific m6Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues 

● Mu, Z;Wiehe, K;Saunders, KO;Henderson, R;Cain, DW;Parks, R;Martik, D;Mansouri, K;Edwards, RJ;Newman, A;Lu, X;Xia, SM;Bonsignori, M;Montefiori, D;Han, Q;Venkatayogi, S;Evangelous, T;Wang, Y;Rountree, W;Tam, Y;Barbosa, C;Munir Alam, S;Williams, WB;Pardi, N;Weissman, D;Haynes, BF; . Ability of nucleoside-modified mRNA to encode HIV-1 envelope trimer nanoparticles 

● Martinez, DR;Schaefer, A;Leist, SR;De la Cruz, G;West, A;Atochina-Vasserman, EN;Parks, R;Barr, M;Li, D;Yount, B;Saunders, KO;Weissman, D;Haynes, BF;Montgomery, SA;Baric, RS; . Chimeric spike mRNA vaccines protect against sarbecovirus challenge in mice



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