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自噬研究相关抗体推荐!

2021-05-17
浏览次数: 303
自噬研究相关抗体推荐!


Autophagy in human health and diseases
自噬研究相关抗体推荐!



Autophagy contributes to basal physiological homeostasis by regenerating metabolic precursors and clearing subcellular debris. Deregulation of this process has been implicated in many diseases, including cancer, metabolic and neuro degenerative disorders, and cardiovascular and pulmonary diseases. Shown above, the diagram reports the publication trends for the study of autophagy. However, clinical targeting of autophagy in human diseases is limited due to an obscure of how autophagy contributes to pathogenesis. Exploration of the mechanisms underlying this autophagy process may lead to the identification of new targets for clinical utility.
Please find the list below for a collection of autophagy molecules associated with human diseases.
For a complete catalogs of autophagy antibodies from GeneTex, visit our website at 

http://www.genetex.com/Web/News/Autophagy-332

 




 Gene
 Antibody
 Association
 BECN1
 Beclin 1 antibody (GTX113039)
 Breast, ovarian, and prostate cancers
 UVRAG
 UVRAG antibody (GTX129111)
 Colon cancers
 ATG1 
 ULK1 antibody (GTX128064)
 Major autophagy initiator
 ATG9
 ATG9A antibody (GTX128427)
 Assists in autophagosomal assembly
 ATG5
 ATG5 antibody (GTX113309)
 Systemic lupus erythematosus, asthma, and lung dysfunction
 ATG16L1
 ATG16L1 antibody (GTX129098)
 Chrohn's disease
 NOD2
 NOD2 antibody (GTX30694)
 Chrohn's disease, and mycobacterium leprae infection
 IRGM
 IRGM antibody (GTX85038)
 Chrohn's disease, and M. tuberculosis infection
 LAMP2
 LAMP2 antibody (GTX103214)
 Danon's cardiomyopathy
 PARK2
 Parkin antibody (GTX25667)
 Parkinson's disease, colon, lung and breast cancers
 SQSTM1
 SQSTM1 antibody (GTX100685)
 Paget's disease
 SMURF1
 SMURF1 antibody (GTX89472)
 Ulcerative colitis


Reference
N Engl J Med. 2013 Feb 14;368(7):651-62





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