产品描述:
5'-pApA is a linearized form of cyclic di-AMP, a bacterial second messenger that activates the host innate immune system through stimulator of interferon genes (STING).{24607, 50984,61373,61374} It is a metabolite of cyclic di-AMP (Item No. 17753) formed via hydrolysis by various phosphodiesterases (PDEs).{61375} 5'-pApA is intended for use as a negative control for cyclic di-AMP signaling.