产品描述:
Iturin A-2 is a cyclic lipopeptide that has been found in B. subtilis and has diverse biological activities.{51484,51485,51486,51487} It is active against the plant pathogenic fungus P. expansum (MIC = 8 µg/disk).{51484} Iturin A-2 induces cytotoxicity in MCF-7 and BT474 breast cancer and HeLa cervical cancer cells (IC50s = 66.81, 95.04, and 77.5 µg/ml, respectively).{51485} It reduces southern corn leaf blight lesion area induced by B. maydis in greenhouse studies when applied at concentrations of 100 and 300 mg/kg AI and reduces the incidence of southern corn leaf blight in field studies at 300 and 500 mg/kg AI.{51486} Iturin A-2 (12.5 µg/ml) inhibits cell division, but not nuclear division, in isolated fertilized starfish eggs.{51487}