您好，欢迎光临欣博盛生物科技商城！
服务热线：400 680 0892
购物车图片 购物车 ( )
Imeglimin (hydrochloride)
品牌： Cayman
产品货号： 37556-50 mg
规格： 50 mg

报价：
折后价：

数量： - +
问题咨询
官网链接
说明书
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
  • 产品名称:
    Imeglimin (hydrochloride)
  • 别名:
  • 产品描述:
    Imeglimin is an anti-hyperglycemic compound.{69519} It inhibits high-glucose- or tert-butyl hydroperoxide-induced cell death in HMEC-1 endothelial cells when used at a concentration of 100 µM. Imeglimin (100 µM) reduces tert-butyl hydroperoxide-induced cytochrome c levels, as well as mitochondrial membrane permeability without affecting mitochondrial respiration, in HMEC-1 cells. It decreases plasma glucose levels and increases plasma insulin levels in a rat model of high-fat diet-induced obesity when administered at a dose of 150 mg/kg.{69520} Imeglimin (100 mg/kg) also reduces colonic balloon-induced pain-related muscle contractions in rats.{69521} In vivo, imeglimin (100 mg/kg) reduces colonic hyperpermeability in a rat model of LPS-induced irritable bowel syndrome (IBS), an effect that can be reversed by the AMP-activated protein kinase (AMPK) inhibitor compound C (dorsomorphin; Item Nos. 11967 | 21207) or the peroxisome proliferator-activated receptor γ (PPARγ) antagonist GW 9662 (Item No. 70785). Formulations containing imeglimin have been used in the treatment of type 2 diabetes.
  • 反应种属:
  • 宿主来源:
  • 实验应用:
  • 靶标/特异性:
  • 同种型:
  • 推荐稀释度:
  • 免疫原:
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
  • 纯化方式:
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    155.2
  • 产品形式:
    A solid
  • 存储溶液:
  • 有效期:
    1460
  • 产地:
    美国
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
  • 产品特点:
  • 纯度:
    ≥95%
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
    775351-61-6
  • 分子式:
    C6H13N5 • XHCl
  • 溶解度:
  • PubChem CID:
关注欣博盛公众号
Copyright ©2021 - 2023 深圳欣博盛生物科技有限公司
粤ICP备08007346号
  网站地图
犀牛云提供企业云服务