产品描述:
Antibiotic. Potent, competitive and specific aminopeptidase inhibitor. Can be administered in vitro to cultured cells or in vivo with low toxicity. Inhibits aminopeptidase B, aminopeptidase N, leucine aminopeptidase and the aminopeptidase activity of leukotriene A4 (LTA4) hydrolase. It is selective for these aminopeptidases over aminopeptidase A, trypsin, chymotrypsin, elastase, papain, pepsin and thermolysin. Immunomodulator. Displays immunostimulant activity via activation of macrophages and T lymphocytes. Displays anticancer and anti-inflammatory activity. Shown to inhibit proliferation, migration and invasion, and induces autophagy and apoptosis in cancer cells. Inhibits the production of LTB4 in erythrocytes. Has been used as useful tool to assess the physiological role of certain mammalian exopeptidases in the regulation of the immune system, the growth of tumors and their invasion of surrounding tissues and the degradation of cellular proteins.