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cGAS Inhibitor Screening Assay Kit
品牌: Cayman
产品货号: 701930-96 strip wells
规格: 96 strip wells

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数量: - +
产品详情
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  • 产品名称:
    cGAS Inhibitor Screening Assay Kit
  • 别名:
    2'3'-cGAMP Synthase|C6orf150|Cyclic GMP-AMP Synthase
  • 产品描述:
    Cayman’s cGAS Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human cGAS, which is a cytosolic dsDNA sensor that detects microbial pathogens. The assay directly measures 2’3’-cGAMP produced by cGAS in the presence of DNA, ATP, and GTP. The cyclic dinucleotide product of that reaction is quantified via ELISA using a 2’3’-cGAMP-specific antiserum. The cGAS inhibitor CU-76 is included as a positive control. The ELISA portion of Cayman’s cGAS Inhibitor Screening Assay Kit is a competitive assay with a range of 4.57-10,000 pM, a midpoint of approximately 300 pM (50% B/B0), and a sensitivity (80% B/B0) of approximately 50 pM.
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    -80
  • 运输温度:
    -80
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  • 有效期:
    180
  • 产地:
    美国
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    Animal/Bovine|Animal/Rabbit
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