-
产品名称:
Amlodipine besylate
-
别名:
2-[(2-Aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5- pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate; Norvasc; Amdepin; Amdipin; Amlodin
-
产品描述:
Amlodipine is a long acting calcium channel antagonist that selectively inhibits calcium ion influx across cell membranes. It acts at the voltage gated calcium channel of the CaV1 or L-type class. It targets L-type calcium channels in muscle cells and N-type calcium channels in the central nervous system which are involved in nociceptive signalling and pain perception. Amlodipine is also an antihypertensive agent that inhibits calcium ion influx across cell membranes, with a greater effect on vascular smooth muscle cells. This causes vasodilation and a reduction in peripheral vascular resistance, thus lowering blood pressure. Its effects on cardiac muscle also prevent excessive constriction in the coronary arteries. Amlodipine has been shown to inhibit proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells.
-
反应种属:
-
宿主来源:
Synthetic.
-
实验应用:
-
靶标/特异性:
-
同种型:
-
推荐稀释度:
-
免疫原:
-
免疫原种属:
-
克隆性:
-
克隆号:
-
纯化方式:
-
偶联:
-
产品浓度:
-
表达系统:
-
阳性对照:
-
保存温度:
-20°C
-
运输温度:
Ambient
-
细胞定位:
-
预期分子量:
567.05
-
产品形式:
solid
-
存储溶液:
-
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
-
产地:
瑞士
-
外观:
-
生产商:
-
功能与背景:
-
URL:
-
灵敏度:
-
检测范围:
-
检测方法:
-
样本类型:
-
产品特点:
-
纯度:
>98% (HPLC)
-
生物活性:
-
内毒素水平:
-
来源:
-
表达方式:
-
Accession #:
-
CAS号:
111470-99-6
-
分子式:
C20H25ClN2O5 . C6H5SO3H
-
溶解度:
-
PubChem CID: