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产品名称:
Empagliflozin
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别名:
Jardiance; BI-10773; (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
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产品描述:
Antidiabetic agent. Potent and selective sodium glucose co-transporter 2 (SGLT-2) inhibitor. >300-fold selectivity over SGLT-1, 4, 5 and 6. SGLT-2 is found almost exclusively in the proximal tubules of nephronic components in kidneys. Inhibition of SGLT-2 reduces blood glucose by blocking renal glucose reabsorption and thereby increasing urinary glucose excretion (UGE). Shown to preserves beta cell mass and restore glucose homeostasis.
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阳性对照:
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保存温度:
-20°C
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运输温度:
Ambient
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细胞定位:
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预期分子量:
450.9
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产品形式:
solid
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有效期:
Stable for at least 3 years after receipt when stored at -20°C.
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产地:
瑞士
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纯度:
>98% (HPLC)
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CAS号:
864070-44-0
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分子式:
C23H27ClO7
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