产品描述:
FMF-04-159-2 is an inhibitor of TAIRE family kinases.{67700} It binds to Cdk14 and Cdk16 (IC50s = 88 and 10.1 nM, respectively) and selectively inhibits Cdk14, Cdk16, Cdk17, and Cdk18 over a panel of 16 additional kinases at 1 µM but does inhibit Cdk2 and Cdk10 by greater than 70% at 1 µM.