产品描述:
Loxoprofen-SRS is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.5 and 0.39 for recombinant human COX-1 and COX-2, respectively) and an active metabolite of the prodrug loxoprofen (Item No. 35088).{61942} Intravenous administration of loxoprofen-SRS inhibits acetic acid-induced writhing, reduces carrageenan-induced mechanical hyperalgesia, and decreases carrageenan-induced paw edema in rats (ED50s = 0.43, 1.28, and 8.01 mg/kg, respectively).{72305}