产品描述:
3-keto Ursolic acid is a triterpenoid that has been found in Z. jujuba and has diverse biological activities.{72095,72096} It inhibits the proliferation of, and colony formation by, MG-63 osteosarcoma cells when used at 10 and 20 µM.{72095} 3-keto Ursolic acid inhibits protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase (IC50s = 11.68 and 61.85 µM, respectively).{72096} It inhibits glucose- and fructose-induced advanced glycation end product (AGE) formation in a cell-free assay when used at a concentration of 50 µM. 3-keto Ursolic acid (25, 50, and 100 µM) increases glucose uptake in insulin-resistant C2C12 mouse skeletal muscle myoblasts.