产品描述:
Rosuvastatin lactone is the lactone form of the HMG-CoA reductase inhibitor rosuvastatin (Item Nos. 12029 | 18813).{59946} It is found in vivo following rosuvastatin administration.{59947} Rosuvastatin lactone is an inhibitor of the cytochrome P450 (CYP) isoforms CYP2C9.1 and CYP2C9.3 (IC50s = 8.52 and 4.1 µM, respectively).{59946}