产品描述:
HDAC6 is a predominantly cytoplasmic enzyme that targets α-tubulin, cortactin, and heat shock protein 90, as well as other substrates.{26999} In this way, it impacts development, proliferation, invasion, and tumorigenesis.{26999} HDAC6 Inhibitor is a potent and selective inhibitor of HDAC6 (IC50 = 36 nM) that poorly blocks other HDAC enzymes.{24174} It is cell permeable, inhibiting the acetylation of tubulin in cells with an IC50 value of 210 nM.{24174}