产品描述:
Ethionamide-d3 is intended for use as an internal standard for the quantification of ethionamide (Item No. 23714) by GC- or LC-MS. Ethionamide is an antimycobacterial compound that is active against M. tuberculosis (MICs = 0.3-1.25 µg/ml).{41216,41215} It is activated via oxidation by flavin monooxygenase and inhibits the InhA enzyme involved in mycolic acid biosynthesis.{41216} Formulations containing ethionamide have been used in the second-line treatment of multi-drug resistant tuberculosis.