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NADPH Cytochrome P450 Reductase (human, recombinant)
品牌: Cayman
产品货号: 33015
规格: 50 µg

报价:
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数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    NADPH Cytochrome P450 Reductase (human, recombinant)
  • 别名:
    CPR|CYPOR|NADPH Hemoprotein Reductase|NCPR|P450R|POR
  • 产品描述:
    NADPH cytochrome P450 reductase (POR) is a flavoprotein and key electron donor to cytochrome P450s (CYPs).{67523,67524} It is composed of an N-terminal membrane anchor domain and FMN-binding domain, which is linked to a C-terminal FAD-binding domain and NADPH-binding domain and localized to the cytosolic side of the endoplasmic reticulum.{67525,67523,67526} POR transfers electrons from NADPH through FAD and FMN coenzymes into the iron of the prosthetic heme group of CYPs.{67525,67523} Cortical levels of POR are increased in the APPswe/PSEN1dE9 transgenic mouse model of Alzheimer’s disease.{67527} Deficiency in POR is associated with ambiguous genitalia and the disruption of steroid metabolism in patients with Antley-Bixler syndrome.{67528} Cayman’s NADPH Cytochrome P450 Reductase (human, recombinant) can be used for enzyme activity assays.
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  • 保存温度:
    -80
  • 运输温度:
    -80
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  • 产品形式:
    50 mM potassium phosphate, pH 7.6, with 10% glycerol
  • 存储溶液:
  • 有效期:
    365
  • 产地:
    美国
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  • 纯度:
    ≥90% estimated by SDS-PAGE
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