产品描述:
XY-4 is a derivative of 1-palmitoyl-2-hydroxy-sn-glycero-3-PA (1-palmitoyl LPA; Item No. 10010094) and an agonist of peroxisome proliferator-activated receptor γ (PPARγ).{11199} It induces reporter gene expression in RAW 264.7 macrophages expressing a peroxisome proliferator-response element (PPRE) when used at a concentration of 5 µM. XY-4 does not act as an agonist at lysophosphatidic acid receptor 1 (LPA1), LPA2, or LPA3. It induces platelet aggregation in vitro when used at a concentration of 1 µM.{72044} XY-4 induces carotid artery neointima formation in rats.{72045}