产品描述:
ω-3 Arachidonic acid-d8 contains eight deuterium atoms at the 8, 9, 11, 12, 14, 15, 17, and 18 positions. It is intended for use as an internal standard for the quantification of ω-3 arachidonic acid by GC- or LC-mass spectrometry. ω-3 Arachidonic acid is a rare polyunsaturated fatty acid found in trace amounts in dietary sources. ω-3 fatty acids are now known to be essential for infant growth and development and to protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders.{2166} In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki value of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.{5525}