产品描述:
5β-Tetrahydrocortisol is an endogenous metabolite of hydrocortisone (cortisol; Item No. 20739).{57583,54782} It is also an intermediate in the biosynthesis of β-cortol (Item No. 33412).{54782} It is formed from cortisol by steroid 5β-reductase and is dehydrogenated by 20β-hydroxysteroid dehydrogenase (20β-HSD) to produce β-cortol in the liver.{61459,57583,54782} Urinary levels of 5β-tetrahydrocortisol have been used as a marker for cortisol production and are associated with metabolic syndrome in obese individuals.{54783}