产品描述:
Visnagin is a polyketide synthase-derived furanochromone originally isolated from A. visnaga that has diverse biological activities.{60512,60513,60514,60515,60516} It inhibits the germination and growth of ryegrass (IC50s = 502 and 214 µM, respectively).{60513} Visnagin (100 µg/ml) is cytotoxic to, and induces apoptosis in, HT-144 melanoma cells.{60514} It reduces LPS-stimulated increases in the secretion of TNF-α, IL-1β, and IFN-γ in BV-2 microglial cells when used at concentrations of 50 and 100 µM.{60515} Visnagin (25 mg/kg) protects against cardiomyopathy induced by doxorubicin (Item No. 15007) in mice.{60516}