产品描述:
Varlitinib is an inhibitor of EGFR and HER2 (IC50s = 7 and 2 nM, respectively).{48649,48650} It inhibits cell proliferation (IC50s = In vivo, varlitinib (100 mg/kg) inhibits phosphorylation of EGFR and ERK and reduces tumor weight in an MDA-MB-468 mouse xenograft model.