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Prostaglandin F2α diethyl amide
品牌： Cayman
产品货号： 16023-5 mg
规格： 5 mg

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数量： - +
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  • 产品名称:
    Prostaglandin F2α diethyl amide
  • 别名:
    Dinoprost diethyl amide|PGF2α diethyl amide|PGF2α-NEt2
  • 产品描述:
    Prostaglandin F2α diethyl amide (PGF2α-NEt2) is an analog of PGF2α (Item No. 16010) in which the C-1 carboxyl group has been modified to an N-diethyl amide. PG esters have been shown to have ocular hypotensive activity.{8837} PG N-ethyl amides were recently introduced as alternative PG hypotensive prodrugs.{8941} Studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various PGs to the free acids with a conversion efficiency of about 4 µg/g corneal tissue/hr.{9311} However, we find that dialkyl amides such as PGF2α-NEt2 are inert to corneal amidase activity, and are not converted in any detectable amount to the corresponding free acids. These compounds may therefore be useful tools in elucidating the claim that PG amides have intrinsic intraocular hypotensive activity.
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  • 阳性对照:
  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
    409.6
  • 产品形式:
    A solution in methyl acetate
  • 存储溶液:
  • 有效期:
    730
  • 产地:
    美国
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  • 纯度:
    ≥98%
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  • 分子式:
    C24H43NO4
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