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Zmp1 (M. tuberculosis) (rec.) (His)
品牌： Adipogen
产品货号： AG-40T-0103-C050
规格： 50 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    Zmp1 (M. tuberculosis) (rec.) (His)
  • 别名:
    Zinc Metalloprotease 1; Endopeptidase; Rv0198c
  • 产品描述:
    M13 endopeptidases are single-pass, transmembrane zinc-metallopeptidases responsible in human for the regulation of the biological activity of many hormones and peptides and are involved in many important processes such as blood pressure regulation (Neprilysin or NEP1), cardiovascular development (Endothelin Converting Enzyme-1 or ECE-12), prevention of haemolytic reaction (KELL) and phosphate homeostasis (PHEX). Zmp1 is a soluble enzyme member of the M13 endopeptidases family that plays a key role in Mycobacterium tuberculosis pathogenicity with a still unknown mechanism. Recently, it was shown to suppress inflammasome activation by inhibiting caspase-1 activation, thus preventing processing of pro-IL-1beta into IL-1beta and the consequent phagosome maturation.
  • 反应种属:
  • 宿主来源:
    E. coli
  • 实验应用:
  • 靶标/特异性:
  • 同种型:
  • 推荐稀释度:
  • 免疫原:
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  • 偶联:
  • 产品浓度:
    0.5mg/ml (Lot specific)
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -80°C
  • 运输温度:
    DRY ICE
  • 细胞定位:
  • 预期分子量:
    ~73.9kDa
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In 10mM TRIS-HCl, pH 8.0.
  • 有效期:
    Stable for at least 6 months after receipt when stored at -80°C.
  • 产地:
    瑞士
  • 外观:
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  • 功能与背景:
  • URL:
  • 灵敏度:
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  • 检测方法:
  • 样本类型:
    Liquid. In 10mM TRIS-HCl, pH 8.0.
  • 产品特点:
  • 纯度:
    >98% (SDS-PAGE)
  • 生物活性:
    ~0.5U/mg protein. Active towards the generic fluorogenic substrate for matrix metalloproteinases MMP2/MMP7 (Lit. 1).
  • 内毒素水平:
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