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NMNAT3 (human) (rec.) (His) (highly active)
品牌: Adipogen
产品货号: AG-40T-0093-C010
规格: 10 ug

报价:
折后价:

数量: - +
产品详情
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  • 产品名称:
    NMNAT3 (human) (rec.) (His) (highly active)
  • 别名:
    Nicotinamide Mononucleotide Adenylyltransferase 3; NMN Adenylyltransferase 3; NaMN Adenylyltransferase 3; EC 2.7.7.18; EC 2.7.7.1
  • 产品描述:
    Mitochondrial NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.
  • 反应种属:
  • 宿主来源:
    E. coli
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  • 产品浓度:
    1mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
    ~27kDa (monomer)
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In 50mM TRIS-HCl, pH 8.0, containing 300mM sodium chloride, 1mM DTT and 10% glycerol.
  • 有效期:
    Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
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  • 样本类型:
    Liquid. In 50mM TRIS-HCl, pH 8.0, containing 300mM sodium chloride, 1mM DTT and 10% glycerol.
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
  • 生物活性:
    >2U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1µmol of NAD+ per min.
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