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Human complement C3 (active)
品牌： GeneTex
产品货号： GTX30711-pro
规格： 250μg

报价：
折后价：

数量： - +
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  • 产品名称:
    Human complement C3 (active)
  • 别名:
    complement C3 , AHUS5 , ARMD9 , ASP , C3a , C3b , CPAMD1 , HEL-S-62p
  • 产品描述:
    Native, human C3 complement component. Glycoprotein composed of two non-identical disulfide-bonded subunits with M.W. of 115 kDa (alpha) and 75 kDa (beta). Present in normal human serum at 1.25 mg/ml. Classical and alternative activation pathways of complement converge at C3 step. Activation via either pathway can result in assembly of C3-cleaving enzymes (C3 convertases) on target surfaces. Both C3 convertases cleave the C3 alpha-chain at peptide bond 77 resulting in production of C3a (M.W. 9.083kDa) and C3b fragments (M.W. 180kDa). Released C3a peptide is one of the three complement anaphylatoxins. The nascent C3b fragment can form a covalent ester bond with target surface. This covalent attachment of C3b to target acceptors is required for continuation of complement activation. This protein was purified from Human Serum (negative for HBsAg and for antibodies to HIV and HCV).
  • 反应种属:
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  • 实验应用:
    Functional Assay
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  • 偶联:
    Unconjugated
  • 产品浓度:
    Batch dependent (Please refer to the vial label for the specific concentration.)
  • 表达系统:
    Human Serum
  • 阳性对照:
  • 保存温度:
    Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
  • 运输温度:
    dry ice
  • 细胞定位:
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  • 产品形式:
    Liquid
  • 存储溶液:
    PBS (pH7.2), no preservative.
  • 有效期:
  • 产地:
    美国
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  • 样本类型:
    PBS (pH7.2), no preservative.
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