Acyl-CoA-binding Protein (human) (rec.) (His) MultiPack - 深圳欣博盛生物科技有限公司

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Acyl-CoA-binding Protein (human) (rec.) (His) MultiPack

品牌： Adipogen

产品货号： AG-40B-0197-3050

规格： 3 x 50 ug

报价：

折后价：

数量： - +

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产品名称:

Acyl-CoA-binding Protein (human) (rec.) (His) MultiPack
别名:

ACBP; Diazepam-binding Inhibitor; DBI; Endozepine; EP
产品描述:

Acyl-coenzyme A (CoA)-binding protein (ACBP) is an ubiquitously expressed 86 aa polypeptide that binds medium- and long-chain acyl-CoA esters with very high affinity. It plays a role as an intracellular carrier of acyl-CoA esters and regulates lipid metabolism in the cytoplasm of most cell types. In addition to its function within the cells as acyl-coenzyme A (CoA)-binding protein, ACBP also functions as secreted protein called Diazepam-Binding Inhibitor (DBI) that can interact with the benzodiazepine-binding site of the gamma-aminobutyric acid (GABA) type A receptor, GABAAR, and modulate its activity. ACBP is secreted upon induction of autophagy (energy deficiency) in different organisms including mouse and human. ACBP levels correlate with human body mass index (BMI). Increasing ACBP levels in mice triggers lipogenesis, food intake and weight gain and neutralization of ACBP increases lipolysis, reduces food intake post-starvation and causes weight loss in mice. Obese patients exhibit elevated plasma levels of ACBP, while a reduction in the ACBP mRNA and ACBP plasma protein levels is observed in these patients after an important weight loss. ACBP might be useful for the prevention or treatment of obesity and metabolic syndrome diseases.
反应种属:
宿主来源:

E. coli
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免疫原:
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产品浓度:

1mg/ml after reconstitution
表达系统:
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保存温度:

-20°C
运输温度:

BLUE ICE
细胞定位:
预期分子量:

12kDa (SDS-PAGE); 12kDa (Monomer by SEC)
产品形式:

solid
存储溶液:

Lyophilized. Contains PBS.
有效期:

Stable for at least 6 months after receipt when stored at -20°C.Working aliquots are stable for up to 3 months when stored at -20°C.
产地:

瑞士
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样本类型:

Lyophilized. Contains PBS.
产品特点:
纯度:

>95% (SDS-PAGE)
生物活性:
内毒素水平:

<0.01EU/µg purified protein (LAL test).
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