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Nampt (mouse) (rec.) (enzymatically active)
品牌： Adipogen
产品货号： AG-40B-0179-C050
规格： 50 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    Nampt (mouse) (rec.) (enzymatically active)
  • 别名:
    Visfatin; PBEF; Pre-B Cell Colony Enhancing Factor 1; PBEF1; Nicotinamide Phosphoribosyltransferase; NAmPRTase
  • 产品描述:
    Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt) also known as pre-B cell colony-enhancing factor 1 (PBEF1) or visfatin is the rate-limiting enzyme in the nicotinamide adenine dinucleotide (NAD+) salvage pathway that converts nicotinamide to nicotinamide mononucleotide in mammals to enable NAD+ biosynthesis. In addition it has been shown to be an adipokine that is localized in the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. The recombinant Nampt (mouse) (rec.) (enzymatically active) (Prod. No. AG-40B-0179) shows activity to convert nicotinamide + phosphoribosyltransferase (PRPP) to nicotinamide mononucleotide (NMN). It migrates as a homodimer on a size exclusion chromatography (SEC) column.
  • 反应种属:
  • 宿主来源:
    HEK 293 cells
  • 实验应用:
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  • 推荐稀释度:
  • 免疫原:
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  • 纯化方式:
  • 偶联:
  • 产品浓度:
    Lot dependent.
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -80°C
  • 运输温度:
    DRY ICE
  • 细胞定位:
  • 预期分子量:
    ~55kDa (SDS-PAGE); ~100-110 kDa (Dimer) (SEC)
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. Contains PBS.
  • 有效期:
    Stable for at least 6 months after receipt when stored at -80°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. Contains PBS.
  • 产品特点:
  • 纯度:
    >90% (SDS-PAGE)
  • 生物活性:
    1µg to 5µg of Nampt (mouse) (rec.) (enzymatically active) show activity in a colorimetric Nampt assay.
  • 内毒素水平:
    <0.01EU/µg purified protein (LAL test).
  • 来源:
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  • PubChem CID:
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