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产品名称:
PEDF (mouse) (rec.)
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别名:
Pigment Epithelium-derived Factor; Stromal Cell-derived Factor 3; Serpin F1; Caspin
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产品描述:
Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.
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反应种属:
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宿主来源:
CHO cells
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实验应用:
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靶标/特异性:
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同种型:
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推荐稀释度:
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免疫原:
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免疫原种属:
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克隆性:
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克隆号:
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纯化方式:
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偶联:
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产品浓度:
0.1mg/ml after reconstitution
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表达系统:
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阳性对照:
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保存温度:
-20°C
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运输温度:
BLUE ICE
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细胞定位:
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预期分子量:
~47kDa (SDS-PAGE)
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产品形式:
solid
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存储溶液:
Lyophilized. Contains PBS.
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有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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产地:
瑞士
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外观:
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功能与背景:
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URL:
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灵敏度:
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检测范围:
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检测方法:
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样本类型:
Lyophilized. Contains PBS.
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产品特点:
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纯度:
>95% (SDS-PAGE)
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生物活性:
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内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
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