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产品名称:
IGFL3 (human) (rec.)
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别名:
Insulin Growth Factor-like Family Member 3
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产品描述:
Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
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反应种属:
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宿主来源:
HEK 293 cells
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实验应用:
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靶标/特异性:
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同种型:
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推荐稀释度:
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免疫原:
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免疫原种属:
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克隆性:
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纯化方式:
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偶联:
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产品浓度:
0.1mg/ml after reconstitution
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表达系统:
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阳性对照:
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保存温度:
-20°C
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运输温度:
BLUE ICE
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细胞定位:
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预期分子量:
~15-17kDa (SDS-PAGE); ~100kDa (Hexamer) by SEC
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产品形式:
solid
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存储溶液:
Lyophilized. Contains PBS.
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有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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产地:
瑞士
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外观:
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URL:
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灵敏度:
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检测方法:
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样本类型:
Lyophilized. Contains PBS.
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产品特点:
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纯度:
>95% (SDS-PAGE)
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生物活性:
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内毒素水平:
<0.5EU/µg purified protein (LAL test; Lonza).
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