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APRIL (mouse) (H98) (multimeric) (rec.)
品牌： Adipogen
产品货号： AG-40B-0035-C010
规格： 10 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    APRIL (mouse) (H98) (multimeric) (rec.)
  • 别名:
    MultimericAPRIL™; ACRP30headless:APRIL; ACRP30headless:CD256; ACRP30headless:TNFSF13; ACRP30headless:A-proliferation-inducing Ligand:
  • 产品描述:
    APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth, is involved in monocyte/macrophage-mediated immunological processes and functions as an important survival factor for plasmablasts and bone marrow plasma cells. MultimericAPRIL™ is a high activity construct in which two trimeric APRIL ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively stimulates proliferation B cell. A basic amino acid sequence (QKQKKQ) close to the NH2 terminus of APRIL is required for binding to negatively charged sulfated glycosaminoglycan side chains of proteoglycans. Proteoglycans mediate binding of APRIL to tumor cells as well as primary lymphoid cells.
  • 反应种属:
  • 宿主来源:
    CHO cells
  • 实验应用:
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  • 推荐稀释度:
  • 免疫原:
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  • 偶联:
  • 产品浓度:
    0.1mg/ml after reconstitution
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
    ~32kDa (SDS-PAGE)
  • 产品形式:
    solid
  • 存储溶液:
    Lyophilized. Contains PBS + 0.5% Trehalose.
  • 有效期:
    Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 检测方法:
  • 样本类型:
    Lyophilized. Contains PBS + 0.5% Trehalose.
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
  • 生物活性:
    Stimulates B cell proliferation.
  • 内毒素水平:
    <0.01EU/µg purified protein (LAL test; Lonza).
  • 来源:
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