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GITRL, Soluble (human) (rec.) (His)
品牌： Adipogen
产品货号： AG-40A-0024T-C050
规格： 50 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    GITRL, Soluble (human) (rec.) (His)
  • 别名:
    Glucocorticoid-induced TNF Receptor Ligand; AITRL; Activation-inducible TNF-related Ligand; TNFSF18
  • 产品描述:
    GITRL (Glucocorticoid-induced TNF receptor ligand) is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.
  • 反应种属:
  • 宿主来源:
    HEK 293 cells
  • 实验应用:
  • 靶标/特异性:
  • 同种型:
  • 推荐稀释度:
  • 免疫原:
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  • 纯化方式:
  • 偶联:
  • 产品浓度:
    After reconstitution:for 10µg size: 0.1mg/mlfor 50µg size: 1 mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
    ~17kDa (SDS-PAGE)
  • 产品形式:
    solid
  • 存储溶液:
    Lyophilized from 0.2µm-filtered solution in PBS.
  • 有效期:
    Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Lyophilized from 0.2µm-filtered solution in PBS.
  • 产品特点:
  • 纯度:
    >90% (SDS-PAGE)
  • 生物活性:
  • 内毒素水平:
    <0.06EU/µg purified protein (LAL test; Lonza).
  • 来源:
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  • PubChem CID:
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