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Tim-4 (mouse):Fc (mouse) (rec.)
品牌： Adipogen
产品货号： CHI-MF-110T4-C100
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    Tim-4 (mouse):Fc (mouse) (rec.)
  • 别名:
    TIM4; TIMD4; T Cell Immunoglobulin and Mucin Domain-containing Protein 4
  • 产品描述:
    Mouse T cell immunoglobulin and mucin domain-containing protein 4, also known as T cell membrane protein 4, TIMD4 and TIM4 is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and TIM family. TIM4 contains one Ig-like V-type (immunoglobulin-like) domain. It is expressed on dendritic cells and macrophages. TIM4 plays an important role in the proliferation of T helper type 2 (Th2) cells. TIM4 is involved in regulating T cell proliferation and lymphotoxin signaling. It is a ligand for HAVCR1 / TIMD1. The expression of TIM4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIM4 and TIM1 are phosphatidylserine receptors for the engulfment of apoptotic cells and may also be involved in intercellular signaling in which exosomes are involved. Modulation of TIM4 production in dendritic cells (DCs) represents a novel therapeutic approach for the treatment of peanut allergy.
  • 反应种属:
  • 宿主来源:
    HEK 293 cells
  • 实验应用:
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  • 免疫原:
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  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
    ~85kDa (SDS-PAGE)
  • 产品形式:
    solid
  • 存储溶液:
    Lyophilized from 0.2µm-filtered solution in PBS.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 检测方法:
  • 样本类型:
    Lyophilized from 0.2µm-filtered solution in PBS.
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
  • 生物活性:
    Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells.
  • 内毒素水平:
    <5EU/mg protein (LAL test; Lonza).
  • 来源:
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