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Semaphorin-4A (mouse):Fc (human) (rec.)
品牌： Adipogen
产品货号： CHI-MF-111SEMA4-C100
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    Semaphorin-4A (mouse):Fc (human) (rec.)
  • 别名:
    Sema4a; Semaphorin-B; Sema B
  • 产品描述:
    Semaphorin 4A (Sema4A, previously semB) is a Class 4 transmembrane Semaphorin with activity in the immune and nervous systems. Sema4A was first described as a molecule that enhances T cell activation and interacts with TIM2 (T cell immunoglobulin and mucin domain 2). Mice with targeted disruption of Sema4A show defects in dendritic cellmediated T cell priming and Th1 responses. Roles for Sema4A have also been identified in the brain, the endothelium and the eye. It mediates hippocampal neuron growth cone collapse in vitro through interaction of the sema domain with plexinB1. Interaction of Sema4A with endothelial cell plexinD1 causes opposition to the angiogenic, proliferative, chemotactic and integrin mediated adhesive actions of VEGF.
  • 反应种属:
  • 宿主来源:
    CHO cells
  • 实验应用:
  • 靶标/特异性:
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  • 推荐稀释度:
  • 免疫原:
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  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    solid
  • 存储溶液:
    Lyophilized from 0.2µm-filtered solution in PBS.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 功能与背景:
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  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Lyophilized from 0.2µm-filtered solution in PBS.
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
  • 生物活性:
  • 内毒素水平:
    <0.06EU/µg protein (LAL test; Lonza).
  • 来源:
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