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CD200 (human):Fc (human) (rec.) (non-lytic)
品牌： Adipogen
产品货号： CHI-HF-220CD200-C100
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    CD200 (human):Fc (human) (rec.) (non-lytic)
  • 别名:
    OX-2 Membrane Glycoprotein; MOX1; MOX2
  • 产品描述:
    CD200, also known as OX-2, is a 45 kDa transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. CD200 knockout mice are characterized by increased macrophage number and activation and are predisposed to autoimmune disorders. In T cells, CD200 functions as a costimulatory molecule independent of the CD28 pathway. Several viruses encode CD200 homologs which are expressed on infected cells during the lytic phase. Like CD200 itself, viral CD200 homologs also suppress myeloid cell activity, enabling increased viral propagation.
  • 反应种属:
  • 宿主来源:
    CHO cells
  • 实验应用:
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  • 免疫原:
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  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    solid
  • 存储溶液:
    Lyophilized from 0.2µm-filtered solution in PBS.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 检测方法:
  • 样本类型:
    Lyophilized from 0.2µm-filtered solution in PBS.
  • 产品特点:
  • 纯度:
    >98% (SDS-PAGE)
  • 生物活性:
    Shows the biological function of the CD200 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
  • 内毒素水平:
    <1EU/mg protein (LAL test; Lonza).
  • 来源:
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