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Fc (human):FLT3 Ligand (human) (rec.)
品牌： Adipogen
产品货号： AG-40B-0119-C100
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    Fc (human):FLT3 Ligand (human) (rec.)
  • 别名:
    FMS-like Tyrosine Kinase 3 Ligand
  • 产品描述:
    FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice. FLT3L induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3L is crucial for steady-state pDC (plasmacytoid dendritic cells) and cDC (classical dendritic cells) development. Deficiency of FLT3L causes a dramatic decrease in DC numbers, whereas increasing its availability increase in DC numbers.
  • 反应种属:
  • 宿主来源:
    CHO cells
  • 实验应用:
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  • 偶联:
  • 产品浓度:
    1mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In PBS (sterile).
  • 有效期:
    Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 灵敏度:
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  • 检测方法:
  • 样本类型:
    Liquid. In PBS (sterile).
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
  • 生物活性:
    In vitro and in vivo generation of conventional and plasmacytoid dendritic cells (DC). FLT3L increases in vivo both NK and DC cells numbers in the spleen when mice are injected intraperitoneally with 2 or 10 µg, daily for 10 days (slightly higher effect at 10 µg).
  • 内毒素水平:
    <0.1EU/µg purified protein (LAL test; Lonza).
  • 来源:
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