您好，欢迎光临欣博盛生物科技商城！
服务热线：400 680 0892
购物车图片 购物车 ( )
BAFF-R (human):Fc (human) (rec.) MultiPack
品牌： Adipogen
产品货号： AG-40B-0027-3050
规格： 3 x 50 ug

报价：
折后价：

数量： - +
问题咨询
官网链接
说明书
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
  • 产品名称:
    BAFF-R (human):Fc (human) (rec.) MultiPack
  • 别名:
    TNFRSF 13C; Tumor Necrosis Factor Receptor Superfamily Member 13C; BR3; BlySR3; CD268; BAFF Receptor
  • 产品描述:
    BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation . Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome , Rheumatoid Arthritis (RA) , Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE) . BAFF is also increased levels in some lymphoid cancers.
  • 反应种属:
  • 宿主来源:
    HEK 293 cells
  • 实验应用:
  • 靶标/特异性:
  • 同种型:
  • 推荐稀释度:
  • 免疫原:
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
  • 纯化方式:
  • 偶联:
  • 产品浓度:
    1mg/ml after reconstitution
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
    ~40kDa (SDS-PAGE)
  • 产品形式:
    solid
  • 存储溶液:
    Lyophilized. Contains PBS.
  • 有效期:
    Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Lyophilized. Contains PBS.
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
  • 生物活性:
    Inhibits BAFF activity. Detection of membrane-bound human and mouse BAFF in combination with PAb to human IgG1.
  • 内毒素水平:
    <0.01EU/µg purified protein (LAL test; Lonza).
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
关注欣博盛公众号
Copyright ©2021 - 2023 深圳欣博盛生物科技有限公司
粤ICP备08007346号
  网站地图
犀牛云提供企业云服务