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Animal-Free Recombinant Human TNF-alpha
品牌： PeproTech
产品货号： AF-300-01A-50ug
规格： 50ug

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数量： - +
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  • 产品名称:
    Animal-Free Recombinant Human TNF-alpha
  • 别名:
    Tumor Necrosis Factor, TNFSF2, Cachectin, Differentiation-inducing factor (DIF), Necrosin, Cytotoxin
  • 产品描述:
    TNF-alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells, including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands, and signals through two receptors, TNFR1 and TNFR2. TNF-alpha is cytotoxic to a wide variety of tumor cells, and is an essential factor in mediating the immune response against bacterial infections. TNF-alpha also plays a role in the induction of septic shock, autoimmune diseases, rheumatoid arthritis, inflammation, and diabetes. Human and murine TNF-alpha demonstrate significant cross-species reactivity. TNF-alpha exists in two forms; a type II transmembrane protein, and a mature soluble protein. The TNF-alpha transmembrane protein is proteolytically cleaved to yield a soluble, biologically active, 17 kDa TNF-alpha, which forms a non-covalently linked homotrimer in solution. Recombinant Human TNF-alpha is a soluble 157 amino acid protein (17.4 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein.
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  • 宿主来源:
    E.coli
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  • 推荐稀释度:
    请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
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  • 预期分子量:
    17.4 kDa
  • 产品形式:
    Standard
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  • 产地:
    美国
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