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CCL5 (human) (rec.) (His)
品牌： Adipogen
产品货号： CHI-HR-200CCL5-C050
规格： 50 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    CCL5 (human) (rec.) (His)
  • 别名:
    C-C Motif Chemokine 5; Eosinophil Chemotactic Cytokine; EoCP; Small-inducible Cytokine A5; T Cell-specific Protein P228; TCP228; T Cell-specific Protein RANTES
  • 产品描述:
    CCL5, also known as RANTES (Regulated upon Activation Normal T cell Expressed and Secreted), is an 8kDa beta-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. Human and mouse RANTES exhibit cross-species activity on human and mouse cells. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4 and CCR5. In humans, CCR5 binding to CCL5 inhibits the infectivity of R5 (M-tropic) but not X4 (T-tropic) strains of HIV-1. The deposition of CCL5 on activated vascular endothelial cells is crucial for monocyte adhesion to damaged vasculature, but CCL5 oligomerization is not required for the extravasation of adherent leukocytes. CCL5 is upregulated in breast cancer and promotes tumor progression through the attraction of proinflammatory macrophages in addition to its actions on tumor cells, stromal cells and the vasculature.
  • 反应种属:
  • 宿主来源:
    E. coli
  • 实验应用:
  • 靶标/特异性:
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  • 推荐稀释度:
  • 免疫原:
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  • 纯化方式:
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  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    solid
  • 存储溶液:
    Lyophilized from 0.2µm-filtered solution in PBS (pH 7.4).
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 功能与背景:
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  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Lyophilized from 0.2µm-filtered solution in PBS (pH 7.4).
  • 产品特点:
  • 纯度:
    >98% (SDS-PAGE)
  • 生物活性:
  • 内毒素水平:
    <0.1EU/µg protein (LAL test; Lonza).
  • 来源:
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  • 分子式:
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  • PubChem CID:
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