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IL-33 (human) (rec.) (untagged) MultiPack
品牌： Adipogen
产品货号： AG-40B-0038-5010
规格： 5 x 10 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    IL-33 (human) (rec.) (untagged) MultiPack
  • 别名:
    Interleukin-33; IL-1F11; NF-HEV
  • 产品描述:
    Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
  • 反应种属:
  • 宿主来源:
    E. coli
  • 实验应用:
  • 靶标/特异性:
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  • 推荐稀释度:
  • 免疫原:
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  • 纯化方式:
  • 偶联:
  • 产品浓度:
    0.1mg/ml after reconstitution
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
    ~18kDa
  • 产品形式:
    solid
  • 存储溶液:
    Lyophilized. Contains PBS.
  • 有效期:
    Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 灵敏度:
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  • 检测方法:
  • 样本类型:
    Lyophilized. Contains PBS.
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
  • 生物活性:
    Activates human and mouse ST2-dependent NF-kappaB pathway.
  • 内毒素水平:
    <0.01EU/µg purified protein (LAL test; Lonza).
  • 来源:
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