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DNA Methylation ELISA Kit
品牌： Cayman
产品货号： 589324-96 strip wells
规格： 96 strip wells

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  • 产品名称:
    DNA Methylation ELISA Kit
  • 别名:
    5-Methyl-2'-deoxycytidine EIA Kit
  • 产品描述:
    DNA methylation is an important epigenetic process regulating gene expression. Methylation occurs on carbon 5 of 2'-deoxy-cytidine yielding the modified base 5-methyl-2'-deoxy cytidine. The methylation pattern of cells is tightly regulated during development with the methylation profile being transmitted from parent to daughter cells during cell division. Methylation results in long-term silencing of genes, while unmethylated regions of DNA can be actively transcribed. Global changes in methylation can be quantified by measuring plasma or urinary levels of 5-methyl-2'-deoxy cytidine. These changes in methylation can provide valuable information about cancer status of an individual. For example, patients with leukemia excrete significantly elevated levels of 5-methyl-2'-deoxy cytidine compared to healthy individuals. Global methylation within tissues can be measured in a similar manner, allowing study of tissue-specific changes that occur as a result of differentiation, aging, or carcinogenesis. Cayman’s DNA Methylation ELISA Kit is a competitive assay that can be used for the quantification of 5-methyl-2'-deoxy cytidine in urine, culture supernatants, plasma, and other sample matrices. The ELISA typically displays IC50 (50% B/B0) and IC80 (80% B/B0) values of approximately 12 and 3 ng/ml, respectively.
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  • 保存温度:
    -20
  • 运输温度:
    -20
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  • 有效期:
    365
  • 产地:
    美国
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    Animal/Goat|Animal/Bovine|Animal/Eel|Animal/Mouse
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