SARS-CoV/SARS-CoV-2 Spike Glycoprotein RBD Chimeric Monoclonal Antibody (Clone D003)

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品牌： Cayman

产品货号： 31990-50 µl

规格： 50 µl

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折后价：

数量： - +

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产品名称:

SARS-CoV/SARS-CoV-2 Spike Glycoprotein RBD Chimeric Monoclonal Antibody (Clone D003)
别名:

SARS-CoV/SARS-CoV-2 Spike RBD|SARS-CoV/SARS-CoV-2 Spike Receptor Binding Domain|SARS-CoV/SARS-CoV-2 Surface Glycoprotein RBD|SARS-CoV/SARS-CoV-2 Surface Glycoprotein Receptor Binding Domain|Severe Acute Respiratory Syndrome Coronavirus/Severe Acute Respiratory Syndrome Coronavirus 2 Spike Glycoprotein Receptor Binding Domain
产品描述:

Severe acute respiratory syndrome coronavirus (SARS-CoV) spike glycoprotein, also known as the surface glycoprotein, is a viral structural protein encoded by the S gene in SARS-CoV RNA that contains the receptor binding domain (RBD).{53462} SARS-CoV is a member of the Betacoronavirus genus of viruses and has an approximately 79% sequence identity with SARS-CoV-2, the causative agent of COVID-19.{53459,53461} SARS-CoV spike glycoprotein is a transmembrane glycoprotein that assembles into homotrimers on the virus surface and is composed of an N-terminal S1 subunit, which contains the receptor binding domain (RBD), and a C-terminal S2 subunit, which facilitates fusion between viral and host cell membranes.{46767,46768,49561} The 193-amino acid RBD of the SARS-CoV spike protein is a target for neutralizing antibodies.{46768,49525} The SARS-CoV RBD, which spans amino acid residues 318 to 510, is 73% identical to that of SARS-CoV-2 and can bind to human angiotensin-converting enzyme 2 (ACE2), which is the host cell surface receptor for both SARS-CoV and SARS-CoV-2.{46768,46767,49525,49561} SARS-CoV is the causative agent of SARS, a primarily respiratory illness characterized by fever, cough, shortness of breath, and an approximately 10% fatality rate.{53461} Cayman's SARS-CoV/SARS-CoV-2 Spike Glycoprotein RBD Chimeric Monoclonal Antibody (Clone D003) is composed of human IgG1κ constant domains and variable regions from a mouse immunized with purified recombinant SARS-CoV spike glycoprotein RBD. It can be used for ELISA, flow cytometry (FC), immunocytochemistry (ICC), and immunofluorescence (IF) applications.
反应种属:
宿主来源:

Chimeric Monoclonal Antibody
实验应用:

ELISA, FC, ICC, IF
靶标/特异性:
同种型:

Human IgG1κ
推荐稀释度:
免疫原:

Recombinant C-terminal His-tagged SARS-CoV spike glycoprotein RBD
免疫原种属:
克隆性:
克隆号:

D003
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保存温度:

-80
运输温度:

-80
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产品形式:

50 or 100 µl of protein A-affinity purified monoclonal antibody
存储溶液:
有效期:

365
产地:

美国
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