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SKP2 antibody
品牌: GeneTex
产品货号: GTX66503
规格: 100μl

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    SKP2 antibody
  • 别名:
    S-phase kinase associated protein 2 , FBL1 , FBXL1 , FLB1 , p45
  • 产品描述:
  • 反应种属:
    Human, Mouse, Rat
  • 宿主来源:
    Rabbit
  • 实验应用:
    ICC/IF, WB
  • 靶标/特异性:
  • 同种型:
    IgG
  • 推荐稀释度:
  • 免疫原:
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SKP2 (NP_005974.2).
  • 免疫原种属:
  • 克隆性:
    Polyclonal
  • 克隆号:
  • 纯化方式:
    Purified by affinity chromatography
  • 偶联:
    Unconjugated
  • 产品浓度:
    Batch dependent (Please refer to the vial label for the specific concentration.)
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
  • 运输温度:
    4°C
  • 细胞定位:
  • 预期分子量:
    48
  • 产品形式:
    Liquid
  • 存储溶液:
    PBS pH7.3, 50% Glycerol
  • 有效期:
  • 产地:
    美国
  • 外观:
  • 生产商:
  • 功能与背景:
    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2011]
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    PBS pH7.3, 50% Glycerol
  • 产品特点:
  • 纯度:
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
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  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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