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anti-Lipoma Preferred Partner, pAb (IG-817)
品牌: Adipogen
产品货号: AG-25T-0106-C050
规格: 50 ug

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    anti-Lipoma Preferred Partner, pAb (IG-817)
  • 别名:
    LPP; LIM Domain-containing Preferred Translocation Partner in Lipoma
  • 产品描述:
    Lipoma preferred partner (LPP) is encoded by the preferred fusion partner gene of the high mobility group protein HMGI-C. LPP is frequently affected by chromosomal translocations in a major group of soft tissue lipomas, as well as in a parosteal lipoma and in pulmonary chondroid hamartomas. The resulting fusion proteins comprise three DNA binding domains of HMGI-C fused to two or three C-terminal LIM domains of LPP and a reciprocal product, respectively. Expression of a HMGI-C/LPP fusion protein causes malignant transformation of fibroblasts. Similar to its relatives zyxin and TRIP (thyroid receptor interacting protein 6) / ZRP-1 (zyxin-related protein 1), LPP consists of a N-terminal proline-rich domain followed by three C-terminal LIM domains (double zinc finger structures that are involved in protein-protein interactions). Like the cytoskeletal protein zyxin, LPP localizes to focal adhesions and cell-cell adherens junctions. LPP harbors a nuclear export signal and displays transcriptional activation capacity.
  • 反应种属:
  • 宿主来源:
    Rabbit
  • 实验应用:
    ICC, IP, WB
  • 靶标/特异性:
  • 同种型:
  • 推荐稀释度:
  • 免疫原:
    Recombinant human lipoma preferred partner (LPP) (aa 1-109).
  • 免疫原种属:
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  • 产品浓度:
    500µg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In PBS containing 0.01% sodium azide.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 样本类型:
    Liquid. In PBS containing 0.01% sodium azide.
  • 产品特点:
  • 纯度:
    Antigen affinity purified.
  • 生物活性:
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