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anti-ST2 (human), pAb (ATTO 647N)
品牌： Adipogen
产品货号： AG-25A-0058YTS-T100
规格： 100 tests

报价：
折后价：

数量： - +
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  • 产品名称:
    anti-ST2 (human), pAb (ATTO 647N)
  • 别名:
    Interleukin-1 Receptor-like 1; IL-1 Receptor-like 1; IL1RL1; IL-33 Receptor; Interleukin-33 Receptor
  • 产品描述:
    ST2 is a member of the Toll/IL-1 receptor family. Two forms of the protein exist, a soluble form known as ST2 and a membrane anchored form known as ST2L. The membrane form is expressed by Th2 cells and bone marrow derived mast cells, whereas the soluble form is expressed by serum-stimulated fibroblasts. It binds IL-33 and is structurally similar to IL-1R1. Type 2 innate lymphoid cells (ILC2), originally referred to as natural helper (NH) cells, are a novel target of IL-33. Lung ILC2s participate in the induction of airway inflammation in influenza virus-infected mice and papain-administrated mice. Soluble ST2 plays a role in protecting ILC2 from IL-33 stimulation and thereby maintaining them in a naïve state and might be important for the regulation of several disease. Blocking with anti-ST2 antibodies has been shown to alleviate experimental arthritis and airway inflammation. The IL-33-ST2 axis is is involved across a range of diseases including asthma, allergies, obesity and cardiac disease.
  • 反应种属:
  • 宿主来源:
    Rabbit
  • 实验应用:
    ELISA, FACS, WB
  • 靶标/特异性:
  • 同种型:
  • 推荐稀释度:
  • 免疫原:
    Recombinant human soluble ST2.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
  • 纯化方式:
  • 偶联:
    ATTO 647N
  • 产品浓度:
    1mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    +4°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In PBS containing 0.02% sodium azide.
  • 有效期:
    Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.
  • 产地:
    瑞士
  • 外观:
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  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. In PBS containing 0.02% sodium azide.
  • 产品特点:
  • 纯度:
  • 生物活性:
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  • PubChem CID:
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