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产品名称:
PD-L1 antibody [HL1041]
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别名:
CD274 molecule , B7-H , B7H1 , PD-L1 , PDCD1L1 , PDCD1LG1 , PDL1
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产品描述:
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反应种属:
Human
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宿主来源:
Rabbit
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实验应用:
ICC/IF, IHC-P, WB
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靶标/特异性:
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同种型:
IgG
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推荐稀释度:
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免疫原:
Synthetic peptide encompassing a sequence within the Intracellular domain of human PD-L1. The exact sequence is proprietary.
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免疫原种属:
Human
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克隆性:
Monoclonal
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克隆号:
HL1041
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纯化方式:
Affinity purified by Protein A.
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偶联:
Unconjugated
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产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
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表达系统:
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阳性对照:
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保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
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运输温度:
4°C
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细胞定位:
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预期分子量:
33
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产品形式:
Liquid
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存储溶液:
PBS, no preservative.
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有效期:
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产地:
美国
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外观:
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生产商:
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功能与背景:
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
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URL:
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检测方法:
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样本类型:
PBS, no preservative.
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纯度:
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生物活性:
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