Phosphotyrosine Antibody: FITC - 深圳欣博盛生物科技有限公司

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Phosphotyrosine Antibody: FITC

品牌： Stressmarq

产品货号： SMC-174D-FITC

规格： 100 µg

报价：

折后价：

数量： - +

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产品名称:

Phosphotyrosine Antibody: FITC
别名:

PhosphoTyrosine (pY) Antibody, PhosphoTyrosine (pY) Antibody
产品描述:

Mouse Anti- Phosphotyrosine Monoclonal IgG1
反应种属:

Species Independent
宿主来源:

Mouse
实验应用:

WB | IHC | ICC/IF | IP
靶标/特异性:
同种型:

IgG1
推荐稀释度:

WB (1:1000), IHC (1:100); optimal dilutions for assays should be determined by the user.
免疫原:

Phosphotyrosine, alanine and glyceine in a 1:1:1 ratio polymerized in the presence of keyhole limpet hemocyanin with 1-ethyl-3-(3'-dimentrylaminopropyl) carbodiimide
免疫原种属:
克隆性:

Monoclonal
克隆号:

G104
纯化方式:

Protein G Purified
偶联:

FITC
产品浓度:

1 mg/ml
表达系统:
阳性对照:
保存温度:

Conjugated antibodies should be stored at 4ºC
运输温度:

Blue Ice or 4ºC
细胞定位:
预期分子量:
产品形式:
存储溶液:

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
有效期:
产地:

加拿大
外观:
生产商:
功能与背景:

Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time (3). Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders (4-6). In particular, the phosphorylation of tyrosine is considered one of the key steps in signal transduction and regulation of enzymatic activity (7). Phosphotyrosine can be detected through specific antibodies, and are helpful in facilitating the identification of tyrosine kinase substrates (8).
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样本类型:

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
产品特点:
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