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anti-PD-1 (human), mAb (AG-IHC001)
品牌： Adipogen
产品货号： AG-20B-6020-R100
规格： 100 ul

报价：
折后价：

数量： - +
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  • 产品名称:
    anti-PD-1 (human), mAb (AG-IHC001)
  • 别名:
    CD279; Programmed Cell Death Protein 1
  • 产品描述:
    Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T cell regulators, expressed as a co-receptor on the surface of activated T cells, B cells and macrophages. Several studies have suggested that the PD-1/PD-L1 signaling pathway may be linked to antitumor immunity, as PD-L1 has been shown to induce apoptosis of activated T cells or inhibit activity of cytotoxic T cells. In comparison to CD10 and Bcl-6, PD-1 is expressed by fewer B cells and has therefore been considered a more specific and useful diagnostic marker for angioimmunoblastic T cell lymphoma. Therapies targeted toward the PD-1 receptor have shown remarkable clinical responses in patients with various types of cancer, including non-small-cell lung cancer, melanoma and renal-cell cancer. This antibody is intended to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods. It has been optimized and validated using the BOND-MAX fully automated IHC&ISH stainer (see Protocol).
  • 反应种属:
  • 宿主来源:
    Purified from concentrated hybridoma tissue culture supernatant.
  • 实验应用:
    ELISA, IHC
  • 靶标/特异性:
  • 同种型:
    Mouse IgG2b
  • 推荐稀释度:
  • 免疫原:
    Recombinant human PD-1 fused to a His-tag.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    AG-IHC001
  • 纯化方式:
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    +4°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In Tris Buffer, pH 7.4, containing 1% BSA and <0.1% sodium azide.
  • 有效期:
    Stable for at least 1 year after receipt when stored at +4°C.
  • 产地:
    瑞士
  • 外观:
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  • 功能与背景:
  • URL:
  • 灵敏度:
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  • 检测方法:
  • 样本类型:
    Liquid. In Tris Buffer, pH 7.4, containing 1% BSA and <0.1% sodium azide.
  • 产品特点:
  • 纯度:
    Protein A/G purified.
  • 生物活性:
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