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anti-Fibronectin (EDA), mAb (blocking) (IST-9) (preservative free)
品牌： Adipogen
产品货号： AG-20B-6001PF-C100
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    anti-Fibronectin (EDA), mAb (blocking) (IST-9) (preservative free)
  • 别名:
    FN; Cold-insoluble Globulin; CIG; Fibronectin (EIIIA)
  • 产品描述:
    Fibronectin is a major component of the extracellular matrix that binds to integrins, cell surfaces and various compounds including collagen, fibrin, heparin, DNA and actin. It occurs in two main forms: plasma and cellular fibronectin. EDA (Extra Domain A)-containing cellular fibronectin (EDA-FN) plays a major role in cell adhesion, growth, migration and differentiation and it is important for processes such as wound healing and embryonic development. It is associated with fibroblast differentiation by increasing alpha-SMA expression, collagen deposition, cell contractility and focal adhesion kinase (FAK) activation. EDA-FN promotes cell spread by interacting with the integrins alpha5-beta1, alpha4-beta1 and alpha9-beta1 and has been shown to promote angiogenesis, lymphangiogenesis and metastasis of colorectal tumors. In transformed or tumor-derived cells the EDA segment is about 10-times higher than in fibronectin from normal fibroblasts and it may therefore be a significant marker for malignancy.
  • 反应种属:
  • 宿主来源:
    Purified from concentrated hybridoma tissue culture supernatant.
  • 实验应用:
    ELISA, FUNC (Blocking), ICC, IHC, WB
  • 靶标/特异性:
  • 同种型:
    Mouse IgG1
  • 推荐稀释度:
  • 免疫原:
    Recombinant Extra Domain A (EDA) region of human cellular fibronectin.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    IST-9
  • 纯化方式:
  • 偶联:
  • 产品浓度:
    Lot dependent
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Sterile liquid. In 20mM sodium phosphate buffer, pH7.6 containing 150mM sodium chloride.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Sterile liquid. In 20mM sodium phosphate buffer, pH7.6 containing 150mM sodium chloride.
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
  • 生物活性:
  • 内毒素水平:
  • 来源:
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  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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