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产品名称:
anti-MPC-2, mAb (JCM-1)
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别名:
Mitochondrial Pyruvate Carrier 2; Brain Protein 44
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产品描述:
Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize pyruvate are physically separated from cytosolic pyruvate pools and rely on a membrane transport system to shuttle pyruvate across the impermeable inner mitochondrial membrane (IMM). Two proteins, mitochondrial pyruvate carriers MPC-1 and MPC-2, form a heterooligomeric complex in the IMM to facilitate pyruvate transport. This step is required for mitochondrial pyruvate oxidation and carboxylation-critical reactions in intermediary metabolism that are dysregulated in several common metabolic diseases.
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反应种属:
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宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
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实验应用:
IP, WB
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靶标/特异性:
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同种型:
Mouse IgG2bkappa
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推荐稀释度:
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免疫原:
Peptide coupled to KLH.
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免疫原种属:
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克隆性:
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克隆号:
JCM-1
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纯化方式:
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偶联:
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产品浓度:
1mg/ml
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表达系统:
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阳性对照:
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保存温度:
-20°C
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运输温度:
BLUE ICE
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细胞定位:
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预期分子量:
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产品形式:
liquid
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存储溶液:
Liquid. In PBS containing 25% glycerol and 0.02% sodium azide.
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有效期:
Stable for at least 1 year after receipt when stored at -20°C.
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产地:
瑞士
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样本类型:
Liquid. In PBS containing 25% glycerol and 0.02% sodium azide.
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